False. If you multiply one side by a negative number, the inequality reverses. Or if you multiply each side by zero, there must at least be an equal sign.
When you multiply or divide each side by 2, the signs stay the same. −16 < 4 and −4 < 1. When you multiply or divide by −2, the inequality sign reverses. 16 > −4 and 4 > −1.
